The IASC Guidelines on Mental Health and Psychosocial Support (MHPSS) in Emergency Settings were established in 2007 to protect and improve people’s mental health and psychosocial well-being in the midst of an emergency. Seven years of dissemination, utilization and implementation of the Guidelines in a range of vastly differing contexts has offered an opportunity for reflection, consolidation and mapping of the next steps toward strengthening and improving MHPSS response in emergencies.