This learning brief captures the experience of transitioning a large USAD-funded orphans and vulnerable children (OVC) project from one USAID grantee to another. It shares the key steps and the critical success factors that enabled a smooth transition process, including undertaking project start up, contracting implementing agencies, implementing administrative processes, recruitment and training, and – most importantly – the management of the transfer of a large OVC caseload, with minimum disruption to service provision nor negative impact on beneficiaries.